|
Deep Isoflurane Anesthesia Is
Associated with Alterations in Ion Homeostasis and Specific Na+/K+-ATPase
Impairment in the Rat Brain.
Reiffurth C, Berndt N, Gonzalez Lopez A, Schoknecht K,
Kovács R, Maechler M, Grote Lambers M, Dreier JP, Friedman A, Spies C, Liotta
A.
Anesthesiology. 2023 Jun 1;138(6):611-623. doi:
10.1097/ALN.0000000000004553.
PMID: 36893015
|
|
Quantitative analysis of magnetic
resonance images for characterization of blood-brain barrier dysfunction in
dogs with brain tumors.
Hanael E, Baruch S, Chai O, Lishitsky L, Blum T,
Rapoport K, Ruggeri M, Aizenberg Z, Peery D, Meyerhoff N, Volk HA, De Decker
S, Tipold A, Baumgaertner W, Friedman A, Shamir M.
J Vet Intern Med. 2023 Mar;37(2):606-617. doi:
10.1111/jvim.16654. Epub 2023 Feb 27.
PMID: 36847997 Free PMC
article.
|
|
White-matter correlates of
anxiety: The contribution of the corpus-callosum to the study of anxiety and
stress-related disorders.
Saar-Ashkenazy R, Guez J, Jacob Y, Veksler R, Cohen JE,
Shelef I, Friedman A, Benifla M.
Int J Methods Psychiatr Res. 2022 Nov 29:e1955. doi:
10.1002/mpr.1955. Online ahead of print.
PMID: 36448238
|
|
Stroke-prone salt-sensitive
spontaneously hypertensive rats show higher susceptibility to spreading
depolarization (SD) and altered hemodynamic responses to SD.
Kang EJ, Prager O, Lublinsky S, Oliveira-Ferreira AI,
Reiffurth C, Major S, Müller DN, Friedman A, Dreier JP.
J Cereb Blood Flow Metab. 2023 Feb;43(2):210-230. doi:
10.1177/0271678X221135085. Epub 2022 Nov 3.
PMID: 36329390 Free PMC
article.
|
|
A companion to the preclinical
common data elements and case report forms for in vivo rodent neuroimaging: A
report of the TASK3-WG3 Neuroimaging Working Group of the ILAE/AES Joint
Translational Task Force.
van Vliet EA, Immonen R, Prager O, Friedman A,
Bankstahl JP, Wright DK, O'Brien TJ, Potschka H, Gröhn O, Harris NG.
Epilepsia Open. 2022 Aug 13. doi: 10.1002/epi4.12643.
Online ahead of print.
PMID: 35962745
|
|
Role of autoantibodies and
blood-brain barrier leakage in cognitive impairment in systemic lupus
erythematosus.
Hanly JG, Legge A, Kamintsky L, Friedman A, Hashmi JA,
Beyea SD, Fisk J, Omisade A, Calkin C, Bardouille T, Bowen C, Matheson K,
Fritzler MJ.
Lupus Sci Med. 2022 Jun;9(1):e000668. doi:
10.1136/lupus-2022-000668.
PMID: 35705307 Free PMC
article.
|
|
Resting state functional connectivity
in SLE patients and association with cognitive impairment and blood-brain
barrier permeability.
Hanly JG, Robertson JW, Legge A, Kamintsky L, Aristi G,
Friedman A, Beyea SD, Fisk JD, Omisade A, Calkin C, Bardouille T, Bowen C,
Matheson K, Hashmi JA.
Rheumatology (Oxford). 2023 Feb 1;62(2):685-695. doi:
10.1093/rheumatology/keac343.
PMID: 35699463
|
|
A fluorescein angiography-based
computer-aided algorithm for assessing the retinal vasculature in diabetic
retinopathy.
Abbasnejad A, Tomkins-Netzer O, Winter A, Friedman A,
Cruess A, Serlin Y, Levy J.
Eye (Lond). 2023 May;37(7):1293-1301. doi:
10.1038/s41433-022-02120-4. Epub 2022 May 28.
PMID: 35643792
|
|
Symptoms reported by Canadians
posted in Havana are linked with reduced white matter fibre density.
Aristi G, Kamintsky L, Ross M, Bowen C, Calkin C,
Friedman A, Hashmi JA.
Brain Commun. 2022 Mar 7;4(2):fcac053. doi:
10.1093/braincomms/fcac053. eCollection 2022.
PMID: 35505689 Free PMC
article.
|
|
Craniotomy for acute monitoring of
pial vessels in the rodent brain.
Aboghazleh R, Alkahmous B, Swissa E, Mansoor S,
Friedman A, Prager O.
MethodsX. 2022 Apr 8;9:101694. doi:
10.1016/j.mex.2022.101694. eCollection 2022.
PMID: 35478597 Free PMC
article.
|
|
Spreading depolarizations in
ischaemia after subarachnoid haemorrhage, a diagnostic phase III study.
Dreier JP, Winkler MKL, Major S, Horst V, Lublinsky S,
Kola V, Lemale CL, Kang EJ, Maslarova A, Salur I, Lückl J, Platz J, Jorks D,
Oliveira-Ferreira AI, Schoknecht K, Reiffurth C, Milakara D, Wiesenthal D,
Hecht N, Dengler NF, Liotta A, Wolf S, Kowoll CM, Schulte AP, Santos E,
Güresir E, Unterberg AW, Sarrafzadeh A, Sakowitz OW, Vatter H, Reiner M,
Brinker G, Dohmen C, Shelef I, Bohner G, Scheel M, Vajkoczy P, Hartings JA,
Friedman A, Martus P, Woitzik J.
Brain. 2022 May 24;145(4):1264-1284. doi:
10.1093/brain/awab457.
PMID: 35411920 Clinical
Trial.
|
|
Detection of blood-brain barrier
dysfunction using advanced imaging methods to predict seizures in dogs with
meningoencephalitis of unknown origin.
Hanael E, Baruch S, Chai O, Nir Z, Rapoport K, Ruggeri
M, Eizenberg I, Peery D, Friedman A, Shamir MH.
J Vet Intern Med. 2022 Mar;36(2):702-712. doi:
10.1111/jvim.16396. Epub 2022 Mar 14.
PMID: 35285550 Free PMC
article.
|
|
Reversal of insulin resistance is
associated with repair of blood-brain barrier dysfunction and remission in a
patient with treatment-resistant bipolar depression.
Calkin C, Kamintsky L, Friedman A.
Bipolar Disord. 2022 Aug;24(5):553-555. doi:
10.1111/bdi.13199. Epub 2022 Mar 13.
PMID: 35247029 No abstract
available.
|
|
Telmisartan as an add-on treatment
for dogs with refractory idiopathic epilepsy: a nonrandomized, uncontrolled,
open-label clinical trial.
Hanael E, Chai O, Konstanitin L, Gibeon L, Rapaport K,
Ruggeri M, Friedman A, Shamir MH.
J Am Vet Med Assoc. 2022 Feb 24;260(7):735-740. doi:
10.2460/javma.20.12.0683.
PMID: 35201995
|
|
The effect of a high-polyphenol
Mediterranean diet (Green-MED) combined with physical activity on age-related
brain atrophy: the Dietary Intervention Randomized Controlled Trial
Polyphenols Unprocessed Study (DIRECT PLUS).
Kaplan A, Zelicha H, Yaskolka Meir A, Rinott E, Tsaban
G, Levakov G, Prager O, Salti M, Yovell Y, Ofer J, Huhn S, Beyer F, Witte V,
Villringer A, Meiran N, B Emesh T, Kovacs P, von Bergen M, Ceglarek U, Blüher
M, Stumvoll M, Hu FB, Stampfer MJ, Friedman A, Shelef I, Avidan G, Shai I.
Am J Clin Nutr. 2022 May 1;115(5):1270-1281. doi:
10.1093/ajcn/nqac001.
PMID: 35021194 Free PMC
article. Clinical Trial.
|
|
International Post Stroke Epilepsy
Research Consortium (IPSERC): A consortium to accelerate discoveries in
preventing epileptogenesis after stroke.
Mishra NK, Engel J Jr, Liebeskind DS, Sharma VK, Hirsch
LJ, Kasner SE, French JA, Devinsky O, Friedman A, Dawson J, Quinn TJ, Selim
M, de Havenon A, Yasuda CL, Cendes F, Benninger F, Zaveri HP, Burneo JG,
Srivastava P, Bhushan Singh M, Bhatia R, Vishnu VY, Bentes C, Ferro J, Weiss
S, Sivaraju A, Kim JA, Galovic M, Gilmore EJ, Pitkänen A, Davis K, Sansing
LH, Sheth KN, Paz JT, Singh A, Sheth S, Worrall BB, Grotta JC,
Casillas-Espinos PM, Chen Z, Nicolo JP, Yan B, Kwan P; for International Post
Stroke Epilepsy Research Consortium (IPSERC).
Epilepsy Behav. 2022 Feb;127:108502. doi:
10.1016/j.yebeh.2021.108502. Epub 2021 Dec 27.
PMID: 34968775 No abstract
available.
|
|
Concussion susceptibility is mediated
by spreading depolarization-induced neurovascular dysfunction.
Parker E, Aboghazleh R, Mumby G, Veksler R, Ofer J,
Newton J, Smith R, Kamintsky L, Jones CMA, O'Keeffe E, Kelly E, Doelle K,
Roach I, Yang LT, Moradi P, Lin JM, Gleason AJ, Atkinson C, Bowen C, Brewer
KD, Doherty CP, Campbell M, Clarke DB, van Hameren G, Kaufer D, Friedman A.
Brain. 2022 Jun 30;145(6):2049-2063. doi:
10.1093/brain/awab450.
PMID: 34927674 Free PMC
article.
|
|
Brainstem and Cortical Spreading
Depolarization in a Closed Head Injury Rat Model.
Aboghazleh R, Parker E, Yang LT, Kaufer D, Dreier JP,
Friedman A, van Hameren G.
Int J Mol Sci. 2021 Oct 28;22(21):11642. doi:
10.3390/ijms222111642.
PMID: 34769073 Free PMC
article.
|
|
Paroxysmal slow wave events
predict epilepsy following a first seizure.
Zelig D, Goldberg I, Shor O, Ben Dor S, Yaniv-Rosenfeld
A, Milikovsky DZ, Ofer J, Imtiaz H, Friedman A, Benninger F.
Epilepsia. 2022 Jan;63(1):190-198. doi:
10.1111/epi.17110. Epub 2021 Nov 9.
PMID: 34750812 Free PMC
article.
|
|
Through the Looking Glass:
Insights Into Visualization Pedagogy Through Sentiment Analysis of Peer
Review Text.
Beasley ZJ, Friedman A, Rosen P.
IEEE Comput Graph Appl. 2021 Nov-Dec;41(6):59-70. doi:
10.1109/MCG.2021.3115387. Epub 2021 Dec 10.
PMID: 34559642
|
|
Insulin Resistance and Blood-Brain
Barrier Dysfunction Underlie Neuroprogression in Bipolar Disorder.
Calkin C, McClelland C, Cairns K, Kamintsky L, Friedman
A.
Front Psychiatry. 2021 May 25;12:636174. doi:
10.3389/fpsyt.2021.636174. eCollection 2021.
PMID: 34113269 Free PMC
article.
|
|
Response to: 'Correspondence on
'Blood-brain barrier leakage in systemic lupus erythematosus is associated
with gray matter loss and cognitive impairment'' by Pamuk and Hasni.
Kamintsky L, Beyea SD, Fisk JD, Hashmi JA, Omisade A,
Calkin C, Bardouille T, Bowen C, Quraan M, Mitnitski A, Matheson K, Friedman
A, Hanly JG.
Ann Rheum Dis. 2023 May;82(5):e124. doi:
10.1136/annrheumdis-2021-220057. Epub 2021 Feb 23.
PMID: 33622691 No abstract
available.
|
|
Distorted Optic Nerve Portends
Neurological Complications in Infants With External Hydrocephalus.
Serlin Y, Ben-Arie G, Lublinsky S, Flusser H, Friedman
A, Shelef I.
Front Neurol. 2021 Feb 1;12:596294. doi:
10.3389/fneur.2021.596294. eCollection 2021.
PMID: 33597915 Free PMC
article.
|
|
TMS-Induced Controlled BBB
Opening: Preclinical Characterization and Implications for Treatment of Brain
Cancer.
Vazana U, Schori L, Monsonego U, Swissa E, Pell GS,
Roth Y, Brodt P, Friedman A, Prager O.
Pharmaceutics. 2020 Oct 5;12(10):946. doi: 10.3390/pharmaceutics12100946.
PMID: 33027965 Free PMC
article.
|
|
Blood-brain barrier leakage in
systemic lupus erythematosus is associated with gray matter loss and
cognitive impairment.
Kamintsky L, Beyea SD, Fisk JD, Hashmi JA, Omisade A,
Calkin C, Bardouille T, Bowen C, Quraan M, Mitnitski A, Matheson K, Friedman
A, Hanly JG.
Ann Rheum Dis. 2020 Dec;79(12):1580-1587. doi:
10.1136/annrheumdis-2020-218004. Epub 2020 Oct 1.
PMID: 33004325
|
|
Dual-Targeted Autoimmune Sword in
Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune
antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human
neural cells and T cells.
Levite M, Zelig D, Friedman A, Ilouz N, Eilam R,
Bromberg Z, Ramadhan Lasu AA, Arbel-Alon S, Edvardson S, Tarshish M, Riek LP,
Lako RL, Reubinoff B, Lebendiker M, Yaish D, Stavsky A, Galun E.
J Autoimmun. 2020 Aug;112:102462. doi: 10.1016/j.jaut.2020.102462.
Epub 2020 Apr 10.
PMID: 32561150
|
|
Slow blood-to-brain transport
underlies enduring barrier dysfunction in American football players.
Veksler R, Vazana U, Serlin Y, Prager O, Ofer J, Shemen
N, Fisher AM, Minaeva O, Hua N, Saar-Ashkenazy R, Benou I, Riklin-Raviv T,
Parker E, Mumby G, Kamintsky L, Beyea S, Bowen CV, Shelef I, O'Keeffe E,
Campbell M, Kaufer D, Goldstein LE, Friedman A.
Brain. 2020 Jun 1;143(6):1826-1842. doi:
10.1093/brain/awaa140.
PMID: 32464655 Free PMC
article.
|
|
The role of spreading
depolarizations and electrographic seizures in early injury progression of the
rat photothrombosis stroke model.
Schoknecht K, Kikhia M, Lemale CL, Liotta A, Lublinsky
S, Mueller S, Boehm-Sturm P, Friedman A, Dreier JP.
J Cereb Blood Flow Metab. 2021 Feb;41(2):413-430. doi:
10.1177/0271678X20915801. Epub 2020 Apr 2.
PMID: 32241203 Free PMC
article.
|
|
Repurposed molecules for
antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Klein P, Friedman A, Hameed MQ, Kaminski RM, Bar-Klein
G, Klitgaard H, Koepp M, Jozwiak S, Prince DA, Rotenberg A, Twyman R, Vezzani
A, Wong M, Löscher W.
Epilepsia. 2020 Mar;61(3):359-386. doi:
10.1111/epi.16450.
PMID: 32196665 Free PMC
article. Review.
|
|
Midazolam and isoflurane
combination reduces late brain damage in the paraoxon-induced status
epilepticus rat model.
Swissa E, Bar-Klein G, Serlin Y, Weissberg I, Kamintsky
L, Eisenkraft A, Statlender L, Shrot S, Rosman Y, Prager O, Friedman A.
Neurotoxicology. 2020 May;78:99-105. doi:
10.1016/j.neuro.2020.02.007. Epub 2020 Feb 18.
PMID: 32084435
|
|
Structural, Molecular, and
Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and
Epilepsy: A Cause, Consequence, or Both?
Löscher W, Friedman A.
Int J Mol Sci. 2020 Jan 16;21(2):591. doi:
10.3390/ijms21020591.
PMID: 31963328 Free PMC
article. Review.
|
|
Paroxysmal slow cortical activity
in Alzheimer's disease and epilepsy is associated with blood-brain barrier
dysfunction.
Milikovsky DZ, Ofer J, Senatorov VV Jr, Friedman AR,
Prager O, Sheintuch L, Elazari N, Veksler R, Zelig D, Weissberg I, Bar-Klein
G, Swissa E, Hanael E, Ben-Arie G, Schefenbauer O, Kamintsky L,
Saar-Ashkenazy R, Shelef I, Shamir MH, Goldberg I, Glik A, Benninger F,
Kaufer D, Friedman A.
Sci Transl Med. 2019 Dec 4;11(521):eaaw8954. doi:
10.1126/scitranslmed.aaw8954.
PMID: 31801888
|
|
Blood-brain barrier dysfunction in
aging induces hyperactivation of TGFβ signaling and chronic yet reversible
neural dysfunction.
Senatorov VV Jr, Friedman AR, Milikovsky DZ, Ofer J,
Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ,
Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H,
Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A,
Friedman A, Kaufer D.
Sci Transl Med. 2019 Dec 4;11(521):eaaw8283. doi:
10.1126/scitranslmed.aaw8283.
PMID: 31801886
|
|
Blood-brain barrier imaging as a
potential biomarker for bipolar disorder progression.
Kamintsky L, Cairns KA, Veksler R, Bowen C, Beyea SD,
Friedman A, Calkin C.
Neuroimage Clin. 2020;26:102049. doi:
10.1016/j.nicl.2019.102049. Epub 2019 Oct 22.
PMID: 31718955 Free PMC
article.
|
|
Blood-brain barrier dysfunction in
status epileptics: Mechanisms and role in epileptogenesis.
Swissa E, Serlin Y, Vazana U, Prager O, Friedman A.
Epilepsy Behav. 2019 Dec;101(Pt B):106285. doi:
10.1016/j.yebeh.2019.04.038. Epub 2019 Nov 8.
PMID: 31711869 Review.
|
|
Dynamic Blood-Brain Barrier
Regulation in Mild Traumatic Brain Injury.
O'Keeffe E, Kelly E, Liu Y, Giordano C, Wallace E,
Hynes M, Tiernan S, Meagher A, Greene C, Hughes S, Burke T, Kealy J, Doyle N,
Hay A, Farrell M, Grant GA, Friedman A, Veksler R, Molloy MG, Meaney JF,
Pender N, Camarillo D, Doherty CP, Campbell M.
J Neurotrauma. 2020 Jan 15;37(2):347-356. doi: 10.1089/neu.2019.6483.
Epub 2019 Nov 8.
PMID: 31702476
|
|
Early blood-brain barrier
dysfunction predicts neurological outcome following aneurysmal subarachnoid
hemorrhage.
Lublinsky S, Major S, Kola V, Horst V, Santos E, Platz
J, Sakowitz O, Scheel M, Dohmen C, Graf R, Vatter H, Wolf S, Vajkoczy P,
Shelef I, Woitzik J, Martus P, Dreier JP, Friedman A.
EBioMedicine. 2019 May;43:460-472. doi:
10.1016/j.ebiom.2019.04.054.
PMID: 31162113 Free PMC
article.
|
|
Combining white matter diffusion
and geometry for tract-specific alignment and variability analysis.
Benou I, Veksler R, Friedman A, Raviv TR.
Neuroimage. 2019 Oct 15;200:674-689. doi:
10.1016/j.neuroimage.2019.05.003. Epub 2019 May 13.
PMID: 31096057
|
|
Blood-brain barrier dysfunction in
canine epileptic seizures detected by dynamic contrast-enhanced magnetic resonance
imaging.
Hanael E, Veksler R, Friedman A, Bar-Klein G, Senatorov
VV Jr, Kaufer D, Konstantin L, Elkin M, Chai O, Peery D, Shamir MH.
Epilepsia. 2019 May;60(5):1005-1016. doi:
10.1111/epi.14739.
PMID: 31032909
|
|
Blood-Brain Barrier Leakage: A New
Biomarker in Transient Ischemic Attacks.
Serlin Y, Ofer J, Ben-Arie G, Veksler R, Ifergane G,
Shelef I, Minuk J, Horev A, Friedman A.
Stroke. 2019 May;50(5):1266-1269. doi: 10.1161/STROKEAHA.119.025247.
PMID: 31009340
|
|
Victims of War:
Dehydroepiandrosterone Concentrations in Hair and Their Associations with
Trauma Sequelae in Palestinian Adolescents Living in the West Bank.
Schindler L, Shaheen M, Saar-Ashkenazy R, Bani Odeh K,
Sass SH, Friedman A, Kirschbaum C.
Brain Sci. 2019 Jan 23;9(2):20. doi:
10.3390/brainsci9020020.
PMID: 30678071 Free PMC
article.
|
|
Seizure-induced microvascular
injury is associated with impaired neurovascular coupling and
blood-brain barrier dysfunction.
Prager O, Kamintsky L, Hasam-Henderson LA, Schoknecht
K, Wuntke V, Papageorgiou I, Swolinsky J, Muoio V, Bar-Klein G, Vazana U,
Heinemann U, Friedman A, Kovács R.
Epilepsia. 2019 Feb;60(2):322-336. doi:
10.1111/epi.14631. Epub 2019 Jan 4.
PMID: 30609012
|
|
Changes of dimension of EEG/ECoG
nonlinear dynamics predict epileptogenesis and therapy outcomes.
Rizzi M, Brandt C, Weissberg I, Milikovsky DZ, Pauletti
A, Terrone G, Salamone A, Frigerio F, Löscher W, Friedman A, Vezzani A.
Neurobiol Dis. 2019 Apr;124:373-378. doi:
10.1016/j.nbd.2018.12.014. Epub 2018 Dec 24.
PMID: 30590177
|
|
Bioenergetic Mechanisms of Seizure
Control.
Kovács R, Gerevich Z, Friedman A, Otáhal J, Prager O,
Gabriel S, Berndt N.
Front Cell Neurosci. 2018 Oct 8;12:335. doi: 10.3389/fncel.2018.00335.
eCollection 2018.
PMID: 30349461 Free PMC
article. Review.
|
|
Evidence for peri-ictal
blood-brain barrier dysfunction in patients with epilepsy.
Rüber T, David B, Lüchters G, Nass RD, Friedman A,
Surges R, Stöcker T, Weber B, Deichmann R, Schlaug G, Hattingen E, Elger CE.
Brain. 2018 Oct 1;141(10):2952-2965. doi:
10.1093/brain/awy242.
PMID: 30239618
|
|
Victims of war-Psychoendocrine
evidence for the impact of traumatic stress on psychological well-being of
adolescents growing up during the Israeli-Palestinian conflict.
Shaheen M, Schindler L, Saar-Ashkenazy R, Bani Odeh K,
Soreq H, Friedman A, Kirschbaum C.
Psychophysiology. 2020 Jan;57(1):e13271. doi:
10.1111/psyp.13271. Epub 2018 Aug 13.
PMID: 30101980
|
|
Concussion, microvascular injury,
and early tauopathy in young athletes after impact head injury and an impact
concussion mouse model.
Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A,
Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON,
Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV Jr, Kondo A, Zhou XZ,
Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE,
Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson
AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall
NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC,
Goldstein LE.
Brain. 2018 Feb 1;141(2):422-458. doi:
10.1093/brain/awx350.
PMID: 29360998 Free PMC
article.
|
|
Epilepsy as a Network Disorder
(1): What can we learn from other network disorders such as autistic spectrum
disorder and mood disorders?
Kanner AM, Scharfman H, Jette N, Anagnostou E, Bernard
C, Camfield C, Camfield P, Legg K, Dinstein I, Giacobbe P, Friedman A,
Pohlmann-Eden B.
Epilepsy Behav. 2017 Dec;77:106-113. doi:
10.1016/j.yebeh.2017.09.014. Epub 2017 Oct 26.
PMID: 29107450 Free PMC
article.
|
|
Epilepsy as a Network Disorder
(2): What can we learn from other network disorders such as dementia and
schizophrenia, and what are the implications for translational research?
Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker
CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J,
Morrison J, Nehlig A, Prasad A, Wilcox KS, Jette N, Pohlmann-Eden B.
Epilepsy Behav. 2018 Jan;78:302-312. doi:
10.1016/j.yebeh.2017.09.016. Epub 2017 Oct 31.
PMID: 29097123 Free PMC
article. Review.
|
|
Quantifying response to
intracranial pressure normalization in idiopathic intracranial hypertension
via dynamic neuroimaging.
Lublinsky S, Kesler A, Friedman A, Horev A, Shelef I.
J Magn Reson Imaging. 2018 Apr;47(4):913-927. doi:
10.1002/jmri.25857. Epub 2017 Sep 27.
PMID: 28960686
|
|
Simulation of spreading
depolarization trajectories in cerebral cortex: Correlation of velocity and
susceptibility in patients with aneurysmal subarachnoid hemorrhage.
Milakara D, Grozea C, Dahlem M, Major S, Winkler MKL,
Lückl J, Scheel M, Kola V, Schoknecht K, Lublinsky S, Friedman A, Martus P,
Hartings JA, Woitzik J, Dreier JP.
Neuroimage Clin. 2017 Sep 6;16:524-538. doi:
10.1016/j.nicl.2017.09.005. eCollection 2017.
PMID: 28948141 Free PMC
article.
|
|
Spreading depolarization is not an
epiphenomenon but the principal mechanism of the cytotoxic edema in various
gray matter structures of the brain during stroke.
Dreier JP, Lemale CL, Kola V, Friedman A, Schoknecht K.
Neuropharmacology. 2018 May 15;134(Pt B):189-207. doi:
10.1016/j.neuropharm.2017.09.027. Epub 2017 Sep 21.
PMID: 28941738 Review.
|
|
Event-Associated Oxygen
Consumption Rate Increases ca. Five-Fold When Interictal Activity Transforms
into Seizure-Like Events In Vitro.
Schoknecht K, Berndt N, Rösner J, Heinemann U, Dreier
JP, Kovács R, Friedman A, Liotta A.
Int J Mol Sci. 2017 Sep 7;18(9):1925. doi:
10.3390/ijms18091925.
PMID: 28880249 Free PMC
article.
|
|
TGFβ signaling is associated with
changes in inflammatory gene expression and perineuronal net degradation
around inhibitory neurons following various neurological insults.
Kim SY, Senatorov VV Jr, Morrissey CS, Lippmann K,
Vazquez O, Milikovsky DZ, Gu F, Parada I, Prince DA, Becker AJ, Heinemann U,
Friedman A, Kaufer D.
Sci Rep. 2017 Aug 9;7(1):7711. doi:
10.1038/s41598-017-07394-3.
PMID: 28794441 Free PMC
article.
|
|
Neuroinflammation imaging markers
for epileptogenesis.
Koepp MJ, Årstad E, Bankstahl JP, Dedeurwaerdere S,
Friedman A, Potschka H, Ravizza T, Theodore WH, Baram TZ.
Epilepsia. 2017 Jul;58 Suppl 3:11-19. doi:
10.1111/epi.13778.
PMID: 28675560
|
|
Dynamic changes in murine
forebrain miR-211 expression associate with cholinergic imbalances and
epileptiform activity.
Bekenstein U, Mishra N, Milikovsky DZ, Hanin G, Zelig
D, Sheintuch L, Berson A, Greenberg DS, Friedman A, Soreq H.
Proc Natl Acad Sci U S A. 2017 Jun
20;114(25):E4996-E5005. doi: 10.1073/pnas.1701201114. Epub 2017 Jun 5.
PMID: 28584127 Free PMC
article.
|
|
Role of neural barriers in the
pathogenesis and outcome of Streptococcus pneumoniae
meningitis.
Prager O, Friedman A, Nebenzahl YM.
Exp Ther Med. 2017 Mar;13(3):799-809. doi:
10.3892/etm.2017.4082. Epub 2017 Jan 24.
PMID: 28450902 Free PMC
article.
|
|
Imaging blood-brain barrier
dysfunction as a biomarker for epileptogenesis.
Bar-Klein G, Lublinsky S, Kamintsky L, Noyman I,
Veksler R, Dalipaj H, Senatorov VV Jr, Swissa E, Rosenbach D, Elazary N,
Milikovsky DZ, Milk N, Kassirer M, Rosman Y, Serlin Y, Eisenkraft A,
Chassidim Y, Parmet Y, Kaufer D, Friedman A.
Brain. 2017 Jun 1;140(6):1692-1705. doi:
10.1093/brain/awx073.
PMID: 28444141
|
|
Electrocorticographic Dynamics as
a Novel Biomarker in Five Models of Epileptogenesis.
Milikovsky DZ, Weissberg I, Kamintsky L, Lippmann K,
Schefenbauer O, Frigerio F, Rizzi M, Sheintuch L, Zelig D, Ofer J, Vezzani A,
Friedman A.
J Neurosci. 2017 Apr 26;37(17):4450-4461. doi:
10.1523/JNEUROSCI.2446-16.2017. Epub 2017 Mar 22.
PMID: 28330876 Free PMC
article.
|
|
WONOEP appraisal: Biomarkers of
epilepsy-associated comorbidities.
Ravizza T, Onat FY, Brooks-Kayal AR, Depaulis A,
Galanopoulou AS, Mazarati A, Numis AL, Sankar R, Friedman A.
Epilepsia. 2017 Mar;58(3):331-342. doi:
10.1111/epi.13652. Epub 2016 Dec 30.
PMID: 28035782 Free PMC
article. Review.
|
|
WONOEP appraisal: Imaging
biomarkers in epilepsy.
van Vliet EA, Dedeurwaerdere S, Cole AJ, Friedman A,
Koepp MJ, Potschka H, Immonen R, Pitkänen A, Federico P.
Epilepsia. 2017 Mar;58(3):315-330. doi:
10.1111/epi.13621. Epub 2016 Nov 24.
PMID: 27883181 Review.
|
|
Isoflurane prevents acquired
epilepsy in rat models of temporal lobe epilepsy.
Bar-Klein G, Klee R, Brandt C, Bankstahl M, Bascuñana
P, Töllner K, Dalipaj H, Bankstahl JP, Friedman A, Löscher W.
Ann Neurol. 2016 Dec;80(6):896-908. doi:
10.1002/ana.24804.
PMID: 27761920
|
|
Corrigendum: Following a potential
epileptogenic insult, prolonged high rates of nonlinear dynamical regimes of
intermittency type is the hallmark of epileptogenesis.
Rizzi M, Weissberg I, Milikovsky DZ, Friedman A.
Sci Rep. 2016 Oct 14;6:35510. doi: 10.1038/srep35510.
PMID: 27739508 Free PMC
article. No abstract available.
|
|
Following a potential
epileptogenic insult, prolonged high rates of nonlinear dynamical regimes of
intermittency type is the hallmark of epileptogenesis.
Rizzi M, Weissberg I, Milikovsky DZ, Friedman A.
Sci Rep. 2016 Aug 4;6:31129. doi: 10.1038/srep31129.
PMID: 27488140 Free PMC
article.
|
|
Glutamate-Mediated Blood-Brain
Barrier Opening: Implications for Neuroprotection and Drug Delivery.
Vazana U, Veksler R, Pell GS, Prager O, Fassler M,
Chassidim Y, Roth Y, Shahar H, Zangen A, Raccah R, Onesti E, Ceccanti M,
Colonnese C, Santoro A, Salvati M, D'Elia A, Nucciarelli V, Inghilleri M,
Friedman A.
J Neurosci. 2016 Jul 20;36(29):7727-39. doi:
10.1523/JNEUROSCI.0587-16.2016.
PMID: 27445149 Free PMC
article.
|
|
Recording, analysis, and
interpretation of spreading depolarizations in neurointensive care: Review
and recommendations of the COSBID research group.
Dreier JP, Fabricius M, Ayata C, Sakowitz OW,
Shuttleworth CW, Dohmen C, Graf R, Vajkoczy P, Helbok R, Suzuki M, Schiefecker
AJ, Major S, Winkler MK, Kang EJ, Milakara D, Oliveira-Ferreira AI, Reiffurth
C, Revankar GS, Sugimoto K, Dengler NF, Hecht N, Foreman B, Feyen B,
Kondziella D, Friberg CK, Piilgaard H, Rosenthal ES, Westover MB, Maslarova
A, Santos E, Hertle D, Sánchez-Porras R, Jewell SL, Balança B, Platz J,
Hinzman JM, Lückl J, Schoknecht K, Schöll M, Drenckhahn C, Feuerstein D,
Eriksen N, Horst V, Bretz JS, Jahnke P, Scheel M, Bohner G, Rostrup E,
Pakkenberg B, Heinemann U, Claassen J, Carlson AP, Kowoll CM, Lublinsky S,
Chassidim Y, Shelef I, Friedman A, Brinker G, Reiner M, Kirov SA, Andrew RD,
Farkas E, Güresir E, Vatter H, Chung LS, Brennan KC, Lieutaud T, Marinesco S,
Maas AI, Sahuquillo J, Dahlem MA, Richter F, Herreras O, Boutelle MG, Okonkwo
DO, Bullock MR, Witte OW, Martus P, van den Maagdenberg AM, Ferrari MD,
Dijkhuizen RM, Shutter LA, Andaluz N, Schulte AP, MacVicar B, Watanabe T,
Woitzik J, Lauritzen M, Strong AJ, Hartings JA.
J Cereb Blood Flow Metab. 2017 May;37(5):1595-1625.
doi: 10.1177/0271678X16654496. Epub 2016 Jan 1.
PMID: 27317657 Free PMC
article. Review.
|
|
Advances in the development of
biomarkers for epilepsy.
Pitkänen A, Löscher W, Vezzani A, Becker AJ, Simonato
M, Lukasiuk K, Gröhn O, Bankstahl JP, Friedman A, Aronica E, Gorter JA,
Ravizza T, Sisodiya SM, Kokaia M, Beck H.
Lancet Neurol. 2016 Jul;15(8):843-856. doi:
10.1016/S1474-4422(16)00112-5.
PMID: 27302363 Review.
|
|
A potential role for glia-derived
extracellular matrix remodeling in postinjury epilepsy.
Kim SY, Porter BE, Friedman A, Kaufer D.
J Neurosci Res. 2016 Sep;94(9):794-803. doi:
10.1002/jnr.23758. Epub 2016 Jun 5.
PMID: 27265805 Review.
|
|
Epileptiform activity and
spreading depolarization in the blood-brain barrier-disrupted peri-infarct
hippocampus are associated with impaired GABAergic inhibition and synaptic
plasticity.
Lippmann K, Kamintsky L, Kim SY, Lublinsky S, Prager O,
Nichtweiss JF, Salar S, Kaufer D, Heinemann U, Friedman A.
J Cereb Blood Flow Metab. 2017 May;37(5):1803-1819.
doi: 10.1177/0271678X16652631. Epub 2016 Jan 1.
PMID: 27252228 Free PMC
article.
|
|
Acute Stress and Perceptual Load
Consume the Same Attentional Resources: A Behavioral-ERP Study.
Tiferet-Dweck C, Hensel M, Kirschbaum C, Tzelgov J,
Friedman A, Salti M.
PLoS One. 2016 May 19;11(5):e0154622. doi:
10.1371/journal.pone.0154622. eCollection 2016.
PMID: 27196027 Free PMC
article.
|
|
Synaptic plasticity in area CA1 of
rat hippocampal slices following intraventricular application of albumin.
Salar S, Lapilover E, Müller J, Hollnagel JO, Lippmann
K, Friedman A, Heinemann U.
Neurobiol Dis. 2016 Jul;91:155-65. doi:
10.1016/j.nbd.2016.03.008. Epub 2016 Mar 10.
PMID: 26972679
|
|
Angiographic evidence of
proliferative retinopathy predicts neuropsychiatric morbidity in diabetic
patients.
Serlin Y, Shafat T, Levy J, Winter A, Shneck M, Knyazer
B, Parmet Y, Shalev H, Ur E, Friedman A.
Psychoneuroendocrinology. 2016 May;67:163-70. doi:
10.1016/j.psyneuen.2016.02.009. Epub 2016 Feb 12.
PMID: 26907995
|
|
Breakdown of Inter-Hemispheric
Connectivity Is Associated with Posttraumatic Symptomatology and Memory
Impairment.
Saar-Ashkenazy R, Veksler R, Guez J, Jacob Y, Shelef I,
Shalev H, Friedman A, Cohen JE.
PLoS One. 2016 Feb 10;11(2):e0144766. doi:
10.1371/journal.pone.0144766. eCollection 2016.
PMID: 26863536 Free PMC
article.
|
|
Corrigendum: Acute stress
facilitates long-lasting changes in cholinergic gene expression.
Kaufer D, Friedman A, Seidman S, Soreq H.
Nature. 2016 Mar 3;531(7592):126. doi:
10.1038/nature16180. Epub 2015 Nov 25.
PMID: 26605528 No abstract
available.
|
|
Autosomal dominant epilepsy with
auditory features: a new LGI1 family including a phenocopy with cortical
dysplasia.
Klein KM, Pendziwiat M, Cohen R, Appenzeller S, de
Kovel CG, Rosenow F, Koeleman BP, Kuhlenbäumer G, Sheintuch L, Veksler R,
Friedman A, Afawi Z, Helbig I.
J Neurol. 2016 Jan;263(1):11-6. doi:
10.1007/s00415-015-7921-2. Epub 2015 Oct 12.
PMID: 26459092
|
|
Altered processing of visual
emotional stimuli in posttraumatic stress disorder: an event-related
potential study.
Saar-Ashkenazy R, Shalev H, Kanthak MK, Guez J,
Friedman A, Cohen JE.
Psychiatry Res. 2015 Aug 30;233(2):165-74. doi:
10.1016/j.pscychresns.2015.05.015. Epub 2015 Jun 19.
PMID: 26138281
|
|
Differential TGF-β Signaling in
Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice.
Levy N, Milikovsky DZ, Baranauskas G, Vinogradov E,
David Y, Ketzef M, Abutbul S, Weissberg I, Kamintsky L, Fleidervish I,
Friedman A, Monsonego A.
J Immunol. 2015 Aug 15;195(4):1713-22. doi:
10.4049/jimmunol.1401446. Epub 2015 Jul 1.
PMID: 26136430
|
|
In response: Multifactorial basis
of epilepsy in patients with neurocysticercosis.
Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A,
Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A,
Verastegui M, Preux PM, Montano S, Pretell EJ, White AC Jr, Gonzales AE,
Gilman RH, Garcia HH.
Epilepsia. 2015 Jun;56(6):975-6. doi:
10.1111/epi.12986.
PMID: 26040533 Free PMC
article. No abstract available.
|
|
Blood-brain barrier in health and
disease.
Friedman A, Kaufer D.
Semin Cell Dev Biol. 2015 Feb;38:1. doi:
10.1016/j.semcdb.2015.03.006.
PMID: 25868082 No abstract
available.
|
|
Albumin induces excitatory
synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired
epilepsy following blood-brain barrier dysfunction.
Weissberg I, Wood L, Kamintsky L, Vazquez O, Milikovsky
DZ, Alexander A, Oppenheim H, Ardizzone C, Becker A, Frigerio F, Vezzani A,
Buckwalter MS, Huguenard JR, Friedman A, Kaufer D.
Neurobiol Dis. 2015 Jun;78:115-25. doi:
10.1016/j.nbd.2015.02.029. Epub 2015 Mar 30.
PMID: 25836421 Free PMC
article.
|
|
Anatomy and physiology of the
blood-brain barrier.
Serlin Y, Shelef I, Knyazer B, Friedman A.
Semin Cell Dev Biol. 2015 Feb;38:2-6. doi:
10.1016/j.semcdb.2015.01.002. Epub 2015 Feb 11.
PMID: 25681530 Free PMC
article. Review.
|
|
Homeostatic regulation of KCC2
activity by the zinc receptor mZnR/GPR39 during seizures.
Gilad D, Shorer S, Ketzef M, Friedman A, Sekler I,
Aizenman E, Hershfinkel M.
Neurobiol Dis. 2015 Sep;81:4-13. doi:
10.1016/j.nbd.2014.12.020. Epub 2015 Jan 3.
PMID: 25562657 Free PMC
article.
|
|
Neurocysticercosis: A natural
human model of epileptogenesis.
Nash TE, Mahanty S, Loeb JA, Theodore WH, Friedman A,
Sander JW, Singh G, Cavalheiro E, Del Brutto OH, Takayanagui OM, Fleury A,
Verastegui M, Preux PM, Montano S, Pretell EJ, White AC Jr, Gonzales AE,
Gilman RH, Garcia HH.
Epilepsia. 2015 Feb;56(2):177-83. doi:
10.1111/epi.12849. Epub 2014 Dec 23.
PMID: 25534640 Free PMC
article. Review.
|
|
The role of cytosolic
phospholipase A2 α in amyloid precursor protein induction by amyloid beta1-42
: implication for neurodegeneration.
Sagy-Bross C, Kasianov K, Solomonov Y, Braiman A,
Friedman A, Hadad N, Levy R.
J Neurochem. 2015 Mar;132(5):559-71. doi:
10.1111/jnc.13012. Epub 2015 Feb 3.
PMID: 25533654
|
|
Blood-brain barrier imaging in
human neuropathologies.
Veksler R, Shelef I, Friedman A.
Arch Med Res. 2014 Nov;45(8):646-52. doi:
10.1016/j.arcmed.2014.11.016. Epub 2014 Nov 29.
PMID: 25453223 Free PMC
article. Review.
|
|
Imaging blood-brain barrier
dysfunction in football players.
Weissberg I, Veksler R, Kamintsky L, Saar-Ashkenazy R,
Milikovsky DZ, Shelef I, Friedman A.
JAMA Neurol. 2014 Nov;71(11):1453-5. doi:
10.1001/jamaneurol.2014.2682.
PMID: 25383774 No abstract
available.
|
|
sec-Butyl-propylacetamide (SPD)
and two of its stereoisomers rapidly terminate paraoxon-induced status
epilepticus in rats.
Bar-Klein G, Swissa E, Kamintsky L, Shekh-Ahmad T,
Saar-Ashkenazy R, Hubary Y, Shrot S, Stetlander L, Eisenkraft A, Friedman A,
Bialer M.
Epilepsia. 2014 Dec;55(12):1953-8. doi: 10.1111/epi.12838.
Epub 2014 Nov 6.
PMID: 25377630
|
|
How spreading depolarization can
be the pathophysiological correlate of both migraine aura and stroke.
Dreier JP, Reiffurth C, Woitzik J, Hartings JA,
Drenckhahn C, Windler C, Friedman A, MacVicar B, Herreras O; COSBID study
group.
Acta Neurochir Suppl. 2015;120:137-40. doi:
10.1007/978-3-319-04981-6_23.
PMID: 25366613
|
|
Should losartan be administered
following brain injury?
Friedman A, Bar-Klein G, Serlin Y, Parmet Y, Heinemann
U, Kaufer D.
Expert Rev Neurother. 2014 Dec;14(12):1365-75. doi:
10.1586/14737175.2014.972945. Epub 2014 Oct 27.
PMID: 25346269 Review.
|
|
Monitoring stroke progression: in
vivo imaging of cortical perfusion, blood-brain barrier permeability and
cellular damage in the rat photothrombosis model.
Schoknecht K, Prager O, Vazana U, Kamintsky L,
Harhausen D, Zille M, Figge L, Chassidim Y, Schellenberger E, Kovács R,
Heinemann U, Friedman A.
J Cereb Blood Flow Metab. 2014 Nov;34(11):1791-801.
doi: 10.1038/jcbfm.2014.147. Epub 2014 Aug 27.
PMID: 25160672 Free PMC
article.
|
|
Blood-brain barrier dysfunction
can contribute to pharmacoresistance of seizures.
Salar S, Maslarova A, Lippmann K, Nichtweiss J,
Weissberg I, Sheintuch L, Kunz WS, Shorer Z, Friedman A, Heinemann U.
Epilepsia. 2014 Aug;55(8):1255-63. doi:
10.1111/epi.12713. Epub 2014 Jul 3.
PMID: 24995798
|
|
Prevention of organophosphate-induced
chronic epilepsy by early benzodiazepine treatment.
Shrot S, Ramaty E, Biala Y, Bar-Klein G, Daninos M,
Kamintsky L, Makarovsky I, Statlender L, Rosman Y, Krivoy A, Lavon O,
Kassirer M, Friedman A, Yaari Y.
Toxicology. 2014 Sep 2;323:19-25. doi:
10.1016/j.tox.2014.05.010. Epub 2014 Jun 2.
PMID: 24881594
|
|
Losartan prevents acquired
epilepsy via TGF-β signaling suppression.
Bar-Klein G, Cacheaux LP, Kamintsky L, Prager O,
Weissberg I, Schoknecht K, Cheng P, Kim SY, Wood L, Heinemann U, Kaufer D,
Friedman A.
Ann Neurol. 2014 Jun;75(6):864-75. doi:
10.1002/ana.24147. Epub 2014 May 28.
PMID: 24659129 Free PMC
article.
|
|
Reduced corpus-callosum volume in
posttraumatic stress disorder highlights the importance of interhemispheric
connectivity for associative memory.
Saar-Ashkenazy R, Cohen JE, Guez J, Gasho C, Shelef I,
Friedman A, Shalev H.
J Trauma Stress. 2014 Feb;27(1):18-26. doi:
10.1002/jts.21887. Epub 2014 Jan 28.
PMID: 24473965
|
|
Preferential lentiviral targeting
of astrocytes in the central nervous system.
Fassler M, Weissberg I, Levy N, Diaz-Griffero F,
Monsonego A, Friedman A, Taube R.
PLoS One. 2013 Oct 2;8(10):e76092. doi:
10.1371/journal.pone.0076092. eCollection 2013.
PMID: 24098426 Free PMC
article.
|
|
Acetylcholinesterase activity in
the cerebrospinal fluid of dogs with seizures.
Chai O, Sommer A, Zimmerman G, Soreq H, Friedman A,
Bdolah-Abram T, Aroch I, Shamir MH.
Vet J. 2013 Oct;198(1):292-4. doi:
10.1016/j.tvjl.2013.06.027. Epub 2013 Aug 27.
PMID: 23988333
|
|
Novel fluorescein
angiography-based computer-aided algorithm for assessment of retinal vessel
permeability.
Serlin Y, Tal G, Chassidim Y, Parmet Y, Tomkins O,
Knyazer B, Friedman A, Levy J.
PLoS One. 2013 Apr 23;8(4):e61599. doi:
10.1371/journal.pone.0061599. Print 2013.
PMID: 23626701 Free PMC
article.
|
|
Increased susceptibility to
acetylcholine in the entorhinal cortex of pilocarpine-treated rats involves
alterations in KCNQ channels.
Maslarova A, Salar S, Lapilover E, Friedman A, Veh RW,
Heinemann U.
Neurobiol Dis. 2013 Aug;56:14-24. doi:
10.1016/j.nbd.2013.02.016. Epub 2013 Apr 11.
PMID: 23583611
|
|
Quantitative imaging assessment of
blood-brain barrier permeability in humans.
Chassidim Y, Veksler R, Lublinsky S, Pell GS, Friedman
A, Shelef I.
Fluids Barriers CNS. 2013 Feb 7;10(1):9. doi:
10.1186/2045-8118-10-9.
PMID: 23388348 Free PMC
article.
|
|
Impaired neurovascular coupling to
ictal epileptic activity and spreading depolarization in a patient with
subarachnoid hemorrhage: possible link to blood-brain barrier dysfunction.
Winkler MK, Chassidim Y, Lublinsky S, Revankar GS,
Major S, Kang EJ, Oliveira-Ferreira AI, Woitzik J, Sandow N, Scheel M,
Friedman A, Dreier JP.
Epilepsia. 2012 Nov;53 Suppl 6(0 6):22-30. doi:
10.1111/j.1528-1167.2012.03699.x.
PMID: 23134492 Free PMC
article. Review.
|
|
Albumin storage in neoplastic
astroglial elements of gangliogliomas.
Schmitz AK, Grote A, Raabe A, Urbach H, Friedman A, von
Lehe M, Becker AJ, Niehusmann P.
Seizure. 2013 Mar;22(2):144-50. doi:
10.1016/j.seizure.2012.10.014. Epub 2012 Nov 20.
PMID: 23182422 Free PMC
article.
|
|
Detection of cerebral hyperperfusion
syndrome after carotid endarterectomy with CT perfusion.
Schoknecht K, Gabi S, Ifergane G, Friedman A, Shelef I.
J Neuroimaging. 2014 May-Jun;24(3):295-7. doi:
10.1111/j.1552-6569.2012.00773.x. Epub 2012 Nov 19.
PMID: 23163877
|
|
Overview and introduction: the
blood-brain barrier in health and disease.
Abbott NJ, Friedman A.
Epilepsia. 2012 Nov;53 Suppl 6(0 6):1-6. doi:
10.1111/j.1528-1167.2012.03696.x.
PMID: 23134489 Free PMC article.
|
|
Long-lasting pro-ictogenic effects
induced in vivo by rat brain exposure to serum albumin in the absence of
concomitant pathology.
Frigerio F, Frasca A, Weissberg I, Parrella S, Friedman
A, Vezzani A, Noé FM.
Epilepsia. 2012 Nov;53(11):1887-97. doi:
10.1111/j.1528-1167.2012.03666.x. Epub 2012 Sep 17.
PMID: 22984896 Free PMC
article.
|
|
Albumin is taken up by hippocampal
NG2 cells and astrocytes and decreases gap junction coupling.
Braganza O, Bedner P, Hüttmann K, von Staden E,
Friedman A, Seifert G, Steinhäuser C.
Epilepsia. 2012 Nov;53(11):1898-906. doi:
10.1111/j.1528-1167.2012.03665.x. Epub 2012 Sep 11.
PMID: 22967085 Free PMC
article.
|
|
Stress-induced altered
cholinergic-glutamatergic interactions in the mouse hippocampus.
Pavlovsky L, Bitan Y, Shalev H, Serlin Y, Friedman A.
Brain Res. 2012 Sep 7;1472:99-106. doi:
10.1016/j.brainres.2012.05.057. Epub 2012 Jul 14.
PMID: 22796599
|
|
Stimulation of the sphenopalatine
ganglion induces reperfusion and blood-brain barrier protection in the
photothrombotic stroke model.
Levi H, Schoknecht K, Prager O, Chassidim Y, Weissberg
I, Serlin Y, Friedman A.
PLoS One. 2012;7(6):e39636. doi:
10.1371/journal.pone.0039636. Epub 2012 Jun 22.
PMID: 22745798 Free PMC
article.
|
|
Fluoxetine induces vasodilatation
of cerebral arterioles by co-modulating NO/muscarinic signalling.
Ofek K, Schoknecht K, Melamed-Book N, Heinemann U,
Friedman A, Soreq H.
J Cell Mol Med. 2012 Nov;16(11):2736-44. doi:
10.1111/j.1582-4934.2012.01596.x.
PMID: 22697296 Free PMC
article.
|
|
Finding a better drug for
epilepsy: antiinflammatory targets.
Dedeurwaerdere S, Friedman A, Fabene PF, Mazarati A,
Murashima YL, Vezzani A, Baram TZ.
Epilepsia. 2012 Jul;53(7):1113-8. doi:
10.1111/j.1528-1167.2012.03520.x. Epub 2012 Jun 12.
PMID: 22691043 Free PMC
article. Review.
|
|
Acetylcholinesterase loosens the
brain's cholinergic anti-inflammatory response and promotes epileptogenesis.
Gnatek Y, Zimmerman G, Goll Y, Najami N, Soreq H,
Friedman A.
Front Mol Neurosci. 2012 May 18;5:66. doi:
10.3389/fnmol.2012.00066. eCollection 2012.
PMID: 22639569 Free PMC
article.
|
|
Cholinergic-associated loss of
hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive
function in mice.
Berson A, Barbash S, Shaltiel G, Goll Y, Hanin G,
Greenberg DS, Ketzef M, Becker AJ, Friedman A, Soreq H.
EMBO Mol Med. 2012 Aug;4(8):730-42. doi:
10.1002/emmm.201100995. Epub 2012 May 25.
PMID: 22628224 Free PMC
article.
|
|
The role of inflammation in
epileptogenesis.
Vezzani A, Friedman A, Dingledine RJ.
Neuropharmacology. 2013 Jun;69:16-24. doi:
10.1016/j.neuropharm.2012.04.004. Epub 2012 Apr 13.
PMID: 22521336 Free PMC
article. Review.
|
|
Pathophysiology of the
neurovascular unit: disease cause or consequence?
Stanimirovic DB, Friedman A.
J Cereb Blood Flow Metab. 2012 Jul;32(7):1207-21. doi:
10.1038/jcbfm.2012.25. Epub 2012 Mar 7.
PMID: 22395208 Free PMC
article. Review.
|
|
Blood-brain barrier dysfunction,
TGFβ signaling, and astrocyte dysfunction in epilepsy.
Heinemann U, Kaufer D, Friedman A.
Glia. 2012 Aug;60(8):1251-7. doi: 10.1002/glia.22311.
Epub 2012 Feb 29.
PMID: 22378298 Free PMC
article. Review.
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Cliniconeuropathologic
correlations show astroglial albumin storage as a common factor in
epileptogenic vascular lesions.
Raabe A, Schmitz AK, Pernhorst K, Grote A, von der
Brelie C, Urbach H, Friedman A, Becker AJ, Elger CE, Niehusmann P.
Epilepsia. 2012 Mar;53(3):539-48. doi:
10.1111/j.1528-1167.2012.03405.x.
PMID: 22372630 Free PMC
article.
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Emotional brain rhythms and their
impairment in post-traumatic patients.
Cohen JE, Shalev H, Admon R, Hefetz S, Gasho CJ,
Shachar LJ, Shelef I, Hendler T, Friedman A.
Hum Brain Mapp. 2013 Jun;34(6):1344-56. doi:
10.1002/hbm.21516. Epub 2012 Feb 14.
PMID: 22331598 Free PMC
article.
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Role of Blood-Brain Barrier
Dysfunction in Epileptogenesis.
Friedman A, Heinemann U.
In: Noebels JL, Avoli M, Rogawski MA, Olsen RW,
Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies
[Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology
Information (US); 2012.
PMID: 22787606 Free Books
& Documents. Review.
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Brain inflammation as a biomarker
in epilepsy.
Vezzani A, Friedman A.
Biomark Med. 2011 Oct;5(5):607-14. doi:
10.2217/bmm.11.61.
PMID: 22003909 Free PMC
article. Review.
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Blood-brain barrier dysfunction,
status epilepticus, seizures, and epilepsy: a puzzle of a chicken and egg?
Friedman A.
Epilepsia. 2011 Oct;52 Suppl 8(Suppl 8):19-20. doi:
10.1111/j.1528-1167.2011.03227.x.
PMID: 21967353 Free PMC
article.
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Blood-brain barrier breakdown and
blood-brain communication in neurological and psychiatric diseases.
Friedman A, Kaufer D.
Cardiovasc Psychiatry Neurol. 2011;2011:431470. doi:
10.1155/2011/431470. Epub 2011 Jul 6.
PMID: 21747970 Free PMC
article. No abstract available.
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Encephalopathy caused by ablation
of very long acyl chain ceramide synthesis may be largely due to reduced
galactosylceramide levels.
Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL,
Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J,
Raas-Rothschild A, Friedman A, Brügger B, Merrill AH Jr, Futerman AH.
J Biol Chem. 2011 Aug 26;286(34):30022-33. doi:
10.1074/jbc.M111.261206. Epub 2011 Jun 24.
PMID: 21705317 Free PMC
article.
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Molecular cascades that mediate
the influence of inflammation on epilepsy.
Friedman A, Dingledine R.
Epilepsia. 2011 May;52 Suppl 3(0 3):33-9. doi:
10.1111/j.1528-1167.2011.03034.x.
PMID: 21542844 Free PMC
article. Review.
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Blood-brain barrier breakdown
following traumatic brain injury: a possible role in posttraumatic epilepsy.
Tomkins O, Feintuch A, Benifla M, Cohen A, Friedman A,
Shelef I.
Cardiovasc Psychiatry Neurol. 2011;2011:765923. doi:
10.1155/2011/765923. Epub 2011 Feb 22.
PMID: 21436875 Free PMC
article.
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Blood-brain barrier dysfunction in
epileptogenesis of the temporal lobe.
Weissberg I, Reichert A, Heinemann U, Friedman A.
Epilepsy Res Treat. 2011;2011:143908. doi:
10.1155/2011/143908. Epub 2011 Jun 7.
PMID: 22937228 Free PMC
article.
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Blood-brain barrier breakdown as a
therapeutic target in traumatic brain injury.
Shlosberg D, Benifla M, Kaufer D, Friedman A.
Nat Rev Neurol. 2010 Jul;6(7):393-403. doi:
10.1038/nrneurol.2010.74. Epub 2010 Jun 15.
PMID: 20551947 Free PMC
article. Review.
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Blood-brain barrier breakdown as a
novel mechanism underlying cerebral hyperperfusion syndrome.
Ivens S, Gabriel S, Greenberg G, Friedman A, Shelef I.
J Neurol. 2010 Apr;257(4):615-20. doi:
10.1007/s00415-009-5384-z. Epub 2009 Nov 22.
PMID: 20361293 Free PMC
article.
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Breaching the blood-brain barrier
as a gate to psychiatric disorder.
Shalev H, Serlin Y, Friedman A.
Cardiovasc Psychiatry Neurol. 2009;2009:278531. doi:
10.1155/2009/278531. Epub 2009 Aug 27.
PMID: 19936105 Free PMC
article.
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Erythropoietin attenuates
hyperoxia-induced oxidative stress in the developing rat brain.
Sifringer M, Brait D, Weichelt U, Zimmerman G,
Endesfelder S, Brehmer F, von Haefen C, Friedman A, Soreq H, Bendix I,
Gerstner B, Felderhoff-Mueser U.
Brain Behav Immun. 2010 Jul;24(5):792-9. doi:
10.1016/j.bbi.2009.08.010. Epub 2009 Sep 1.
PMID: 19729061
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Astrocytic dysfunction in
epileptogenesis: consequence of altered potassium and glutamate homeostasis?
David Y, Cacheaux LP, Ivens S, Lapilover E, Heinemann
U, Kaufer D, Friedman A.
J Neurosci. 2009 Aug 26;29(34):10588-99. doi:
10.1523/JNEUROSCI.2323-09.2009.
PMID: 19710312 Free PMC
article.
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Dynamic in vivo imaging of
cerebral blood flow and blood-brain barrier permeability.
Prager O, Chassidim Y, Klein C, Levi H, Shelef I,
Friedman A.
Neuroimage. 2010 Jan 1;49(1):337-44. doi:
10.1016/j.neuroimage.2009.08.009. Epub 2009 Aug 12.
PMID: 19682584 Free PMC
article.
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Transcriptome profiling reveals
TGF-beta signaling involvement in epileptogenesis.
Cacheaux LP, Ivens S, David Y, Lakhter AJ, Bar-Klein G,
Shapira M, Heinemann U, Friedman A, Kaufer D.
J Neurosci. 2009 Jul 15;29(28):8927-35. doi: 10.1523/JNEUROSCI.0430-09.2009.
PMID: 19605630 Free PMC
article.
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Blood-brain barrier
breakdown-inducing astrocytic transformation: novel targets for the
prevention of epilepsy.
Friedman A, Kaufer D, Heinemann U.
Epilepsy Res. 2009 Aug;85(2-3):142-9. doi:
10.1016/j.eplepsyres.2009.03.005. Epub 2009 Apr 11.
PMID: 19362806 Free PMC
article. Review.
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Acetylcholine-induced seizure-like
activity and modified cholinergic gene expression in chronically epileptic
rats.
Zimmerman G, Njunting M, Ivens S, Tolner EA, Behrens
CJ, Gross M, Soreq H, Heinemann U, Friedman A.
Eur J Neurosci. 2008 Feb;27(4):965-75. doi:
10.1111/j.1460-9568.2008.06070.x.
PMID: 18333967
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Cholinergic dysfunction in
temporal lobe epilepsy.
Friedman A, Behrens CJ, Heinemann U.
Epilepsia. 2007;48 Suppl 5:126-30. doi:
10.1111/j.1528-1167.2007.01300.x.
PMID: 17910592 Review.
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Pathogenesis of stress-associated
skin disorders: exploring the brain-skin axis.
Pavlovsky L, Friedman A.
Curr Probl Dermatol. 2007;35:136-145. doi: 10.1159/000106420.
PMID: 17641495 Review.
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TGF-beta receptor-mediated albumin
uptake into astrocytes is involved in neocortical epileptogenesis.
Ivens S, Kaufer D, Flores LP, Bechmann I, Zumsteg D,
Tomkins O, Seiffert E, Heinemann U, Friedman A.
Brain. 2007 Feb;130(Pt 2):535-47. doi:
10.1093/brain/awl317. Epub 2006 Nov 21.
PMID: 17121744
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Propagation of interictal
discharges in temporal lobe epilepsy: correlation of spatiotemporal mapping
with intracranial foramen ovale electrode recordings.
Zumsteg D, Friedman A, Wieser HG, Wennberg RA.
Clin Neurophysiol. 2006 Dec;117(12):2615-26. doi:
10.1016/j.clinph.2006.07.319. Epub 2006 Oct 6.
PMID: 17029950
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Coding region paraoxonase
polymorphisms dictate accentuated neuronal reactions in chronic,
sub-threshold pesticide exposure.
Browne RO, Moyal-Segal LB, Zumsteg D, David Y, Kofman
O, Berger A, Soreq H, Friedman A.
FASEB J. 2006 Aug;20(10):1733-5. doi:
10.1096/fj.05-5576fje. Epub 2006 Jun 28.
PMID: 16807370
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Motor inhibition and learning
impairments in school-aged children following exposure to organophosphate
pesticides in infancy.
Kofman O, Berger A, Massarwa A, Friedman A, Jaffar AA.
Pediatr Res. 2006 Jul;60(1):88-92. doi:
10.1203/01.pdr.0000219467.47013.35.
PMID: 16788088
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Source localization of interictal
epileptiform discharges: comparison of three different techniques to improve
signal to noise ratio.
Zumsteg D, Friedman A, Wieser HG, Wennberg RA.
Clin Neurophysiol. 2006 Mar;117(3):562-71. doi:
10.1016/j.clinph.2005.11.014. Epub 2006 Jan 19.
PMID: 16427355
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Source localization of mesial
temporal interictal epileptiform discharges: correlation with intracranial
foramen ovale electrode recordings.
Zumsteg D, Friedman A, Wennberg RA, Wieser HG.
Clin Neurophysiol. 2005 Dec;116(12):2810-8. doi:
10.1016/j.clinph.2005.08.009. Epub 2005 Oct 25.
PMID: 16253551
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Induction of sharp wave-ripple
complexes in vitro and reorganization of hippocampal networks.
Behrens CJ, van den Boom LP, de Hoz L, Friedman A,
Heinemann U.
Nat Neurosci. 2005 Nov;8(11):1560-7. doi:
10.1038/nn1571. Epub 2005 Oct 16.
PMID: 16222227
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Focal cortical dysfunction and
blood-brain barrier disruption in patients with Postconcussion syndrome.
Korn A, Golan H, Melamed I, Pascual-Marqui R, Friedman
A.
J Clin Neurophysiol. 2005 Jan-Feb;22(1):1-9. doi:
10.1097/01.wnp.0000150973.24324.a7.
PMID: 15689708
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Persistent BBB disruption may
underlie alpha interferon-induced seizures.
Pavlovsky L, Seiffert E, Heinemann U, Korn A, Golan H,
Friedman A.
J Neurol. 2005 Jan;252(1):42-6. doi:
10.1007/s00415-005-0596-3.
PMID: 15672209
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Acetylcholinesterase/paraoxonase
interactions increase the risk of insecticide-induced Parkinson's disease.
Benmoyal-Segal L, Vander T, Shifman S, Bryk B, Ebstein
RP, Marcus EL, Stessman J, Darvasi A, Herishanu Y, Friedman A, Soreq H.
FASEB J. 2005 Mar;19(3):452-4. doi:
10.1096/fj.04-2106fje. Epub 2005 Jan 3.
PMID: 15629887
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Lasting blood-brain barrier
disruption induces epileptic focus in the rat somatosensory cortex.
Seiffert E, Dreier JP, Ivens S, Bechmann I, Tomkins O,
Heinemann U, Friedman A.
J Neurosci. 2004 Sep 8;24(36):7829-36. doi:
10.1523/JNEUROSCI.1751-04.2004.
PMID: 15356194 Free PMC
article.
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Long-term seizure outcomes
following amygdalohippocampectomy.
Wieser HG, Ortega M, Friedman A, Yonekawa Y.
J Neurosurg. 2003 Apr;98(4):751-63. doi:
10.3171/jns.2003.98.4.0751.
PMID: 12691400
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Pyridostigmine enhances
glutamatergic transmission in hippocampal CA1 neurons.
Pavlovsky L, Browne RO, Friedman A.
Exp Neurol. 2003 Feb;179(2):181-7. doi:
10.1016/s0014-4886(02)00016-x.
PMID: 12618125
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Alternative splicing and neuritic
mRNA translocation under long-term neuronal hypersensitivity.
Meshorer E, Erb C, Gazit R, Pavlovsky L, Kaufer D,
Friedman A, Glick D, Ben-Arie N, Soreq H.
Science. 2002 Jan 18;295(5554):508-12. doi:
10.1126/science.1066752.
PMID: 11799248
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