Lab Manager
Nanocarriers for siRNA delivery, alginate hydrogel and scaffolds as platform for cells growth
Work Experience
11.2006-now: Lab manager, Laboratory of Prof. Smadar Cohen, Department of Biotechnology, Ben-Gurion University of the Negev.
Use of biomaterials in various applications: bio-inspired nano complexes for siRNA delivery; use of scaffolds as cell matrix in tissue engineering and regenerative medicine
2002-10.2006: Research assistant (Immigrant Absorption funds and extramural funds), Department of Life Sciences, Ben-Gurion University of the Negev. Research on the mechanism of acetohydroxy acid synthase (AHAS)
1997-2001: Manager of microbiology lab in Verena Company, Kiev, Ukraine.
1994-1997: Manager of biology lab in Emcell embryonic tissues center, Kiev, Ukraine. Research is in blood creating cells of human embryonic liver cells.
1985-1994: Microbiology engineer in the institute of microbiology and virology, Science Academy, Kiev, Ukraine. Development is of a microbiology method for detecting micotoxins in food products.
Education:
1980-1985: B.Sc. and M.Sc. in technological engineering of microbiology industry, Technological school of food industry, Kiev, Ukraine.
Selected publication:
Somasekhar Bondalapati, Emil Ruvinov, Olga Kryukov, Smadar Cohen, Ashraf Brik “Rapid End-Group Modification of Polysaccharides for Biomaterial Applications in Regenerative Medicine”
Macromolecular Rapid Communications, 09/2014
Eyal Shteyer, Ami Ben Ya'acov, Lidia Zolotaryova, Avital Sinai, Yoav Lichtenstein, Orit Papoo, Olga Kryukov, Tsiona Elkayam, Smadar Cohen, Yaron Ilan “Reduced liver cell death using a bandage of alginate scaffold: A novel approach for liver reconstruction after extended partial hepatectomy”.
Acta Biomaterialia, 03/2014
Kryukov, O, Ruvinov, E, Cohen, S. 3D Perfusion Cultivation of Human Cardiac derived Progenitors Facilitates their Expansion while Maintaining Progenitor State. Tissue Engineering Part C Methods, 03/ 2014
Dasa Cizkova, Lucia Slovinska, Ivana Grulova, Michel Salzet, Stefan Cikos, Olga Kryukov, Smadar Cohen “The influence of sustained dual-factor presentation on the expansion and differentiation of neural progenitors in affinity-binding alginate scaffolds”. Journal of Tissue Engineering and Regenerative Medicine, 08/2013
Sapir Y, Kryukov O, Cohen S. “Integration of multiple cell-matrix interactions into alginate scaffolds for promoting cardiac tissue regeneration”. Biomaterials, (2011) 32 (7): 1838-1847.
Vyazmensky M., Zherdev Y., Slutzker A., Belenky I., Kryukov O., Barak Z. and Chipman D. M. "Interactions between large and small subunits of different acetohydroxyacid synthase isozymes of Escherichia coli". Biochemistry, (2009).
Vyazmensky M., Engel S., Kryukov O., Berkovich-Berger D., Kaplun L., "Construction of an active acetohydroxyacid synthase I with a flexible linker connecting the catalytic and the regulatory subunits". Biochim. Biophys. Acta, 1764, 955 – 960 (2006).