$$News and Reports$$

Apr. 01, 2025

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Dissolved oxygen is essential for metabolism, growth, and various physiological and pathological processes. However, standard models like organ-on-chip systems often use ambient oxygen levels, which do not accurately reflect the lower levels found in the body. In this study, that was published on the cover of the journal Lab on Chip, Prof. Ben-Yoav's team led by the PhD student Daniel Kaufman​ at Ben-Gurion University, in collaboration with Bahnemann’s group at Augsburg University, developed a microfluidic system that combines electrochemical and optical dissolved oxygen sensors with lab-on-a-chip technology to monitor oxygen levels and generate hydrogen peroxide (H₂O₂), a key reactive oxygen species (ROS).  This platform provides a useful tool for studying custom-made electrodes. In the future, it could help regulate oxygen levels and reactive oxygen species in real time within organ-on-chip systems.

The Ben-Yoav Research Group Web site: https://www.benyoav.com

Professor Hadar Ben-Yoav ​benyoav@bgu.ac.il​​

Full article text is available here.

You may also check the article in the published_dO2.pdf.​​