The DIP project, entitled 'Chemical Proteomics Inside Us: Using Chemical Tools to Decipher Communication Between Bacteria and Humans', focuses on a fundamental question: what happens to the microbiome in our gut when a new bacterial species makes its entrance? How are these Invaders recognized and what is the role of chemical signals that these bacteria secrete, and how are they sensed? Using the powerful tools of chemical proteomics and advanced animal model systems, the team of Michael Meijler (BGU), Eran Elinav (Weizmann Institute) and Matthias Mann (Max Plack Institute) aims to answer this seminal and dynamic puzzle that defines human health and disease.
