Dissolved oxygen is essential for metabolism,
growth, and various physiological and pathological processes. However, standard
models like organ-on-chip systems often use ambient oxygen levels, which do not
accurately reflect the lower levels found in the body. In this study, that was published on the cover of the journal Lab on Chip, Prof. Ben-Yoav's team led by the PhD student Daniel Kaufman at Ben-Gurion University, in collaboration with Bahnemann’s
group at Augsburg University, developed a microfluidic system that combines
electrochemical and optical dissolved oxygen sensors with lab-on-a-chip
technology to monitor oxygen levels and generate hydrogen peroxide (H₂O₂), a
key reactive oxygen species (ROS). This
platform provides a useful tool for studying custom-made electrodes. In the
future, it could help regulate oxygen levels and reactive oxygen species in
real time within organ-on-chip systems.
The Ben-Yoav Research Group Web site: https://www.benyoav.com
Professor Hadar Ben-Yoav benyoav@bgu.ac.il
Full article text is available here.
You may also check the article in the
published_dO2.pdf.