The study of the genetic basis of diseases in defined inbred communities offers a unique opportunity for identifying and characterizing disease-associated genes which are direct causes of clinical disease. The Genetics & Bioinformatics group's research is focused on integrating diverse data types for personalized diagnosis, utilizing protein structure data, understanding and predicting the behavior of complex biological networks and interpretation of high throughput experiments, including expression profiles and next-generation sequencing. It conducts functional genomics and proteomics studies in order to identify new drug targets, to discover novel molecular pathways of disease, to validate mechanisms of actions of drugs, and to develop diagnostic tools for diseases, with a special focus on genetic diseases of the Bedouins population in the Negev.
Group members
