$$Events$$

30 מאי 2022
13:30

בניין לורי לוקיי לכימיה (#43), אולם 015

13:30
התכנסות וכיבוד קל

13:45
דברי פתיחה – פרופ' מיכאל מיילר
דברים בשם משפחת טננבאום - ההורים, אלן ורינה טננבאום

14:00
סמינר מחלקתי
פרופ' דגנית דנינו, מעבדת Cryo-EM לחומר רך, הטכניון - המכון הטכנולוגי הישראלי,
נושא ההרצאה: "Cryo-EM של קולואידים רכים"


Pr​of. Dganit Danino

Cryo-EM Laboratory of Soft Matter, Technion-Israeli Institute of Technology



Cryo-EM of Soft Colloi​​ds

Our research is focused on resolving complex structures an​d dynamic​​ processes of soft colloids using the unique ability of cryo electron microscopy methods, cryo-EM, to simultaneously reveal coexisting structures, capture shortlived intermediates, adirectly illuminate structural details. This information, importantly, relates to the native, bulk state, and is at nanometer resolution. The traditional and leading technique in t​his family, Cryo-TEM, is powerful as it directly and without image processing discloses incredible morphologies and structures that are many times beyond what we could anticipate or imagine. Until recently however, we could only collect single images, 2D projections of the sample volume, and the spatial organizati​​on remained an unexplored domain. With cutting edge technological improvements in detection, and by advancing new methodologies including cryo-electron tomography (Cryo-ET), we can now address questions in colloid science of additional complexity and unfold the 3D organization of soft nanosized colloids in solution. Here we highlight traditional and new directions in Cryo-EM that combined provide clearer and more precise structural, spatial, temporal and quantitative data of colloidal systems, and much improved understanding of structure, properties and function.