A Novel Alginate Hydrogel Based Controlled and Targeted Delivery System
Controlled drug delivery systems offer numerous advantages compared to conventional dosage forms including improved efficacy, reduced toxicity, and improved patient compliance and convenience. Controlled release systems aim to improve the effectiveness of drug therapy

Fertility Preservation in Young Male Cancer Patients
Chemotherapy and radiation treatments for cancer and other conditions can cause permanent infertility. Therefore, patients should take steps to preserve their fertility before initiating gonadotoxic treatments...

A Novel Hydrogel Based Injectable Bilayer Device for Simultaneous Regeneration of Articular Cartilage and Subchondral Bone

A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient's damaged cartilage cannot spontaneously heal itself...


A Potential Drug Target for Amyotrophic Lateral Sclerosis (ALS).pdf

Amyotrophic Lateral Sclerosis (ALS) also named Lou Gehrig's disease, is a fatal neurodegenerative disease characterized by the progressive degeneration of cortical brain neurons, brainstem and, upper and lower motor neurons

Success in the treatment of cancer with chemotherapy is often limited by the non-specific toxicity of anticancer drugs. Current therapeutic approaches to the treatment of cancer are thus focused on developing novel delivery systems to increase the therapeutic efficacy...

Production of the Polyunsaturated Fatty AcidDihomo -G- Linolenic Acid (DGLA) by a Microalgal Strain

The n-6 or Ω-6 essential fatty acids (EFA's) are required in the body for in particular for maintaining normal flexibility, fluidity and permeability of such membranes...

Novel Telomerase Activators

Telomerase is an endogenous enzyme which re-lengthens telomeres. It is present in high concentrations in the fast-growing embryo’s stem cells, and declines with age...

Alginate Biomaterials for Treating

Acute liver failure and chronic liver disease, such as hepatitis and cirrhosis, present a huge unmet medical need, with annual 1-2 million deaths worldwide. The liver is responsible for detoxification-removing and excreting body wastes and hormones, drugs and foreign substances, synthesis of plasma proteins...

Viscosupplementation with Algal Polysaccharides in the Treatment of Arthritis.pdf

Arthritis is chronic inflammation of the joint, accompanied by pain, swelling and limitation of movement in joints and connective tissue. It afflicts more than 40 million people in the United States...

Development of Anti Necrotic Drugs for Prevention and Treatment of Life Threatening Diseases

Cell death can occur through two main mechanisms, apoptosis or necrosis. Apoptosis is a tightly regulated physiological process and many of the biochemical pathways involved are well characterized. Necrosis, the outcome of severe and acute injury, has been until lately generally viewed as an accidental pathological mode of cell death...


Anti-Inflammatory and Anti-Cancer Effects

Natural products of Nuphar lutea ((Nymphaeaceae) have been widely used for treating inflammatory conditions in ethnic medicine. Scientific investigations on the medicinal properties of Nuphar extracts have indicated several potential applications, such as anti-leishmanial, anti-bacterial and anti-cancer activities.


Inflammation induced anti IL1 therapy

Anti interleukin-1 therapy using recombinant IL-1 receptor antagonist (Anakinra) was introduced in 1993 for the treatment of Rheumatoid Arthritis.​

A Dual-Specific Anti-Resorptive Recombinant Protein for Bone Related Disorders.pdf

Osteoporosis (OP) is a common chronic skeletal disorder in aging individuals. In spite of the progress made
in recent years, there is still a great demand for safer and more specific drugs for extended administration.​


A Recombinant Fusion Glucose Dehydrogenase for Glucose Sensing.pdf 

Blood glucose monitoring is an essential daily task of diabetic patients. Most glucose sensing devices, available today, use an enzyme that oxidises glucose. During glucose oxidation, electrons are being released.​


Fragment-Based Virtual Screening for the Detection of New Anti-Infective Drugs​

Too few antibiotics are in the pipeline to tackle the global crisis of drug resistance, which is responsible for the rise of hardly treatable infections around the world as the World Health Organization (WHO) warns. Among the multi-drug resistant bacterial diseases that are increasing and spreading at an alarming pace is Mycobacterium tuberculosis (Mtb), which requires a treatment of between 9 and 24 months.​


 Alginate Biomaterials for Treating liver dysfunction and diseas

Acute liver failure and chronic liver disease, such as hepatitis and cirrhosis, present a huge unmet medical need, with annual 1-2 million deaths worldwide.


Nanoparticles for Intracellular Delivery of Nucleic Acids Therapeutics.pdf

Nucleic acid compounds such as small interference RNA (siRNA), micro RNA (miRNA), antisense RNA, mRNA and decoy oligodeoxynucleotides (ODN) can be used for the therapeutic modulation of gene expression as well as for the replacement of defective or missing genes and proteins.


Phospholipid-Based Prodrug for the Treatment of IBD.pdf 

The global inflammatory bowel diseases (IBD) drug market is estimated at $9.5bn in 2020 with novel therapies expected to be the main drivers of growth.


Succinate Decoy Receptors Succilators as Biological Treatment for IBD and Related Extra Intestinal Symptoms

Succinate is a metabolic intermediate of the tricarboxylic acid (TCA) cycle and a pivotal inflammatory and ischemia-reperfusion signaling molecule. Succinate stimulates the selective G-protein coupled receptor, SUCNR1, which is linked to Diabetes, Hypertension, Arthritis and Inflammatory bowel disease (IBD).

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Vascularized Immunomodulatory Scaffold for Cell Transpalntation V2.pdf

The global market for HSCT, which was US$13.06 billion in 2016, is anticipated to rise at a CAGR of 12.80% and by 2025 reach a value of US$37.61 billion. Allogeneic transplants have emerged as the most valued products in this market and are expected to remain so over the next years.


Acyl-Coa: Diacylglycerol Acyltransferase 1-like Gene (PTDGAT1) and Uses Thereof
A Method of Treating Neurodegenerative Diseases
Amyloid Beta-Peptides and Methods of Use Thereof
Assay for Detecting Circulating Free Nucleic Acids
An Expeditious Synthesis of Ubiquitinated Peptide Conjugates

Cartillage and Bone Regenaration.pdf

Cell Therapy to Neurodegenerative Diseases
Cells containing a nanopatch sensor in their membrane
Chemical Preparation of Ubiqitin Thioesters and Modifications Thereof
Chemical Preparation of Polyubiquitin Chains
Composition Comprising Red Microalgae Polysaccharides and Metals
Detector Comprising a Membrane Perturbation –Detecting Polymer and Functional Membrane Fragments
Desaturases of the Green Microalga and Uses Thereof
Desaturase Defective Mutant Gene Use Thereof
Fragments of NKp44 and Nkp46 for Targeting Viral Infected and Tumor Cells
Methods for Inhibiting Necrosis
Method of Treating Neurological Disorders
Method for Protecting Plants from Stress and Senescence
Novel naphthoquinone derivatives and their use for treating cardiovascular diseases and malignancies
Oil Globule Protein and Uses Thereof
Polyunsaturated Fatty acid Elongase Gene and Uses Thereof
Polydiacetylene Containing Solid Colorimetric Detector, Method for Its Preparation and Uses Thereof
Red Microalgae Expressing Exogenous Polypeptides and Methods of Generating and Utilizing Same
Substituted Cyclohexylidene-Ethyldene-Octahydro-Indene Compounds
Thiamine Pyrophosphate Riboswitch Mutants Producing Vitamin B1 Enriched Food and Feed Crops
Use of NKp46 for Preventing Diabetes
Molybdenum-Converter Based Electron Linear Accelerator and Method for Producing Radioisotopes.pdfMolybdenum-Converter Based Electron Linear Accelerator and Method for Producing Radioisotopes
Anionic Polyplexes For Use In The Delivery Of Nucleic Acids.pdfAnionic Polyplexes For Use In The Delivery Of Nucleic Acids
Cell free protein synthesis with Unnatural Amino Acids.pdfCell free protein synthesis with Unnatural Amino Acids
Compositions and methods for conferring herbicide resistance.pdfCompositions and methods for conferring herbicide resistance
Electrochemical Lateral Flow Bioassay and Biosensor.pdfElectrochemical Lateral Flow Bioassay and Biosensor

Methods for diagnosing cancer and precancerous lesions.pdfMethods for diagnosing cancer and precancerous lesions
Peptide-polypeptide co-assembled nanoparticles for drug delivery.pdfPeptide-polypeptide co-assembled nanoparticles for drug delivery
Poly (Methyl Methacrylate) supported polydiacetylene films as molecular sensing tools.pdfPoly (Methyl Methacrylate) supported polydiacetylene films as molecular sensing tools
Positively Charged Polysccharides for RNA Transfection.pdfPositively Charged Polysccharides for RNA Transfection
Site-Selective Modification of Polysaccharides and Applications thereof.pdfSite-Selective Modification of Polysaccharides and Applications thereof
​​​​Combination of Alpha 1 Antitrypsin and Temporary T Cell Depletion.pdfCombination of Alpha 1 Antitrypsin and Temporary T Cell Depletion