The following labs use molecular biology techniques to study the nervous system in health and disease.
Agam Galila Studies the biological basis of psychiatric disorders and their treatment with a particular focus on the pathophysiology of bipolar disorder and the molecular mechanism of the beneficial effect of lithium salts.
Brodski Claude Studies brain functions and disorders, by investigating the molecular mechanisms controlling the development of the nervous system with a specific focus on the genetic cascades controlling the generation of monoaminergic neurons and its implications for neurological and psychiatric disorders.
Cohen Hagit Studies translational studies of stress-related psychopathology, mainly post-traumatic stress disorder (PTSD) and depression, with specific focus on factors affecting the response of individual test subjects to psychological stress.
Gitler Daniel Studies the mechanisms that control synaptic vesicle dynamics within the presynaptic terminal, and how these affect synaptic function.
Golan Hava Studies the neurobiology of autism and other neuro-developmental disorders with a specific focus on understanding how genetics interact with the in-utero environment to control the development of the brain and how this is altered in certain conditions.
Libersat Frederic Studies the cellular and molecular mechanisms by which parasites control the behavior of their hosts using a cocktail of neurotoxins and neuromodulators.
Fleidervish Ilya Studies how molecular elements, such as voltage-gated channels, are distributed and regulated in their native environment.
Friedman Alon Studies the pathophysiology of several brain disorders and the effects of stress on the nervous system. Human and animal studies focus on dysfunction of the blood-brain barrier in epilepsy and neurodegenerative diseases, developing new imaging methods and novel therapies for the prevention and treatment of injury-related epilepsy and neurodegeneration.
Israelson Adrian Studies the cellular and molecular mechanisms that lead to the onset and progression of neurodegenerative diseases with special emphasis on amyotrophic lateral sclerosis (ALS). Combines biochemistry, molecular biology and use both cellular and in vivo models to investigate the molecular mechanisms involved in ALS pathogenesis. These devastating diseases represent a major challenge to public health worldwide, especially as our population continue to age.
Priel Esther Studies the role of telomerase in the brain including the effects of increasing telomerase on the development and progression of neurodegenerative disease and the role of topoisomerase I in the repair of DNA damage in brain cells.
Monsonego Alon Investigates interactions between the central nervous system and the immune system with a particular emphasis on vaccine and cell-based therapies during advanced stages of development.
Toiber Deborah Investigates how epigenetic modifications and chromatin structure influence DNA repair, the roles of several uncharacterized proteins in the DNA damage signaling have on aging, and brain related diseases, as well as changes in epigenetic modifications and DNA damage in neurodegeneration.
Yifrach Ofer Studies the involvement of voltage-dependent potassium channels in action potential generation, propagation and transmission.
Uzefovsky Florina Studies the biological basis, including genetics and endocrinology, of empathy development in the typical range and atypical range (e.g., autism); and how biological factors interact with environmental influences (social environment, parenting) to shape different trajectories of empathy development.
Zangen Avraham Studies the critical alterations within the brain reward system that are associated with pathological conditions, and how localized electromagnetic stimulation (using TMS) of these networks can affect such conditions in animal models and humans with a specific focus on molecular and electrophysiological alterations in reward-related networks that are associated with and may cause depression, addiction and attention deficit disorders.
Zilberberg Noam Studies the regulation of potassium leak (K2P) channel activity, including the search for specific potassium channel modifiers, the effects of native neurotoxins (isolated from various venoms) on potassium channels, and the development of a screening system for the identification of recombinant channel-blockers.