The following labs use genetic methods to study the nervous system in health and disease:

Brodski Claude Email Icon.jpg Studies brain functions and disorders, by investigating the molecular mechanisms controlling the development of the nervous system with a specific focus on the genetic cascades controlling the generation of monoaminergic neurons and its implications for neurological and psychiatric disorders.

Israelson Adrian Email Icon.jpg Studies the cellular and molecular mechanisms that lead to the onset and progression of neurodegenerative diseases with special emphasis on amyotrophic lateral sclerosis (ALS). Combines biochemistry, molecular biology and use both cellular and in vivo models to investigate the molecular mechanisms involved in ALS pathogenesis. These devastating diseases represent a major challenge to public health worldwide, especially as our population continue to age.

 

Menashe Idan Email Icon.jpg Studies the role of genetic and non-genetic risk factors on the predisposition to autism spectrum disorder (ASD) by applying advanced biostatistics and bioinformatics approaches to large genomics and population-based data.

 

Toiber Deborah Email Icon.jpg Investigates how epigenetic modifications and chromatin structure influence DNA repair,  the roles of several uncharacterized proteins in the DNA damage signaling have on aging, and brain related diseases, as well as changes in  epigenetic modifications and DNA damage in neurodegeneration.

 

Uzefovsky Florina  Email Icon.jpg Studies the biological basis, including genetics and endocrinology, of empathy development in the typical range and atypical range (e.g., autism); and how biological factors interact with environmental influences (social environment, parenting) to shape different trajectories of empathy development.