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Unraveling the structure-function relationships of proteins and molecular complexes is pivotal for an improved understanding of cellular processes. NIBN's applied biotechnology group comprises of prominent scientists and state-of-the-art infrastructure in the fields of microscopy, protein crystallography, protein engineering as well as nano-technology, which has been further strengthened through NIBN's establishment of the Aaron Klug Integrated Centre for Biomolecular Structure and Function. Current efforts include electron tomography (3D electron microscopy) of cells and organelles, understanding magnetosome biology with the intent to generate tailor-made magnetite particles for various nano-  and bio-technological applications, understanding the structural basis of ligand receptor interactions important in drug discovery, optimizing yields of recombinant protein expression with site-specifically incorporated unnatural amino acids and functional genomics and proteomics related to reproduction and calcium biomineralization.

 
Group members